Diazepam is a benzodiazepine drug that increases the activity of gamma-aminobutyric acid (GABA) in the brain and nervous system. This gives a calming and sedative effect.
Diazepam medicine precautions
Diazepam medicine needs to be avoided if you are allergic to its constituents, have glaucoma, muscle problems, hepatic, renal, or respiratory problems, or sleep apnea. Avoid diazepam if you have a history of drug or alcohol abuse and dependence and during pregnancy and lactation.
Diazepam medicine interactions
Diazepam also interacts with HIV protease inhibitors like ritonavir or sodium oxybate. Rifamycins or St. John's wort decreases the effectiveness of diazepam tablets. Hydantoins like phenytoin show increased side effects with diazepam. Avoid using diazepam with disufiram, hormonal contraceptives, monoamine oxidase inhibitors, narcotics, phenothiazines, or other drugs for mental or mood problems as they increase the risk of side effects of diazepam. Azole antifungals, barbiturates, cimetidine, clozapine, diltiazem, macrolide antibiotics, omeprazole, selective serotonin uptake inhibitors, telithromycin, methadone, nefazodone and increases the sedative effect and confusion.
Diazepam medicine uses
Diazepam medicine online may be used for short-term treatment of anxiety, to mitigate muscle spasms, and to decrease the symptoms associated with alcohol withdrawal. In may also be used along with other antiseizure medicines to treat prolonged seizures.
Effectiveness and response
It reaches its peak effect within 1 to 1.5 hours and is metabolized to active metabolites after that. The effects may last for 24 hours or more and it starts accumulating in the body on repeated dosing.
Though diazepam may be used at times to relieve anxiety and seizures, it is highly addictive and its withdrawal symptoms can be devastating.